Best Back 4 Blood Builds

Best Back 4 Blood Builds
Images: WB Games

Written by 

David Coulson

Published 

17th Oct 2021 04:24

The best Back 4 Blood builds utilise the deck system, which means that there are plenty of mechanics involved when it comes to finding the perfect combination. Back 4 Blood is a complex game, but once you know the best builds, you'll be on your way to conquering Nightmare mode. This includes using the best Back 4 Blood cards and best Back 4 Blood characters, along with sussing out the Back 4 Blood supply lines.

For this guide on the best Back 4 Blood builds, we will be focusing on the best Back 4 Blood weapons, as well as the 15 cards you should use in each deck and why. Here are the best Back 4 Blood builds for all eight Cleaners.

Best Back 4 Blood Evangelo Build

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Best Evangelo weapons:

  • Primary weapon - Assault Rifle
  • Secondary weapon - Machete

Best Evangelo deck:

  • Copper Scavenger
  • Battle Lust
  • Second Chance
  • Ridden Slayer
  • Superior Cardio
  • Batter Up
  • Heavy Attack
  • Avenge The Fallen
  • Inspiring Sacrifice
  • Durable
  • Berserker
  • Fresh Bandage
  • Vitamins
  • Tactical Vest
  • Ammo Pouch

Evangelo is a character that is designed to be up close and personal with the horde of Ridden and Mutations. His weapon of choice is a Machete and he has the ability to perform a break out every 60 seconds, so for his build, we chose to leave the Breakout card out of his deck. His abilities are +25% Stamina Regen, and a +5% Team Move Speed boost, which is perfect for Evangelo being able to run into the horde wielding his Machete or run away to create some distance before switching to his Assault Rifle. 

Copper Scavenger is a must-have card as it highlights nearby Copper stashes, as well as spawning more, which makes it easier to buy better weapons, team upgrades, and items such as First Aid Kits at the start of every mission. 

Battle Lust is another great card as it heals the player for two health every time they get a melee kill. Avenge The Fallen and Inspiring Sacrifice are great team boosting cards that give the player more health and better stats should a teammate be incapacitated. You will notice these cards, and a few others, a lot throughout this guide as they are essential for players to use.

Best Back 4 Blood Walker Build

Back 4 Blood Walker Character
Click to enlarge

Best Walker weapons:

  • Primary weapon - Assault Rifle
  • Secondary weapon - SMG

Best Walker deck:

  • Copper Scavenger
  • Combat Knife
  • Two Is One And One Is None
  • Breakout
  • Reckless Strategy
  • Superior Cardio
  • Inspiring Sacrifice
  • Avenge The Fallen
  • Ammo Pouch
  • Ridden Slayer
  • Hi-Vis Sights
  • Reload Drills
  • Front Sight Focus
  • Motorcycle Jacket
  • Antibiotic Ointment

Walker is all about slaying hordes of Ridden, with Precision Kills granting a 20% accuracy boost for five seconds, as well as having a +10% Damage boost and a +10 Team Health boost. His deck should reflect this too, with cards such as Ammo Pouch and Tactical Vest improving his ammo capacity, while cards such as Hi-Vis Sights, and Front Sight Focus help to make gunplay a much faster and enjoyable experience.

For Walker's build, we decided to give him the Two Is One And One Is None card, which allows for a primary weapon to be used as a secondary weapon. While there are secondary SMGs in the game, the primary ones are typically much better, so having the option to use those will really help, and it also gives him the option to swap the SMG for a Shotgun or Sniper Rifle if you feel that suits his play style better.

  • Our top Back 4 Blood tips will help you get through the tougher difficulty settings

Best Back 4 Blood Holly Build

Back 4 Blood Holly Character
Click to enlarge

Best Holly weapons:

  • Primary weapon - Assault Rifle
  • Secondary weapon - Melee Weapon

Best Holly deck:

  • Copper Scavenger
  • Breakout
  • Superior Cardio
  • Batter Up
  • Battle Lust
  • Second Chance
  • Reckless Strategy
  • Inspiring Sacrifice
  • Avenge The Fallen
  • Charitable Soul
  • Slugger
  • Ridden Slayer
  • Motorcycle Jacker
  • Antibiotic Ointment
  • Run And Gun

Holly is best used as a tank-style character who likes to run into hordes of Ridden with all guns blazing. She starts with a Bat as her melee weapon, so we have decided to keep that in her build, although you could swap it for an Axe or Machete if you prefer them. Holly's boosts are that she gains 10 Stamina for each Ridden that she kills, as well as having +10% Damage Resistance, and has a +25 Team Stamina boost. 

Along with the usual cards that you will see throughout these builds, we have also given Holly the Batter Up card, which grants +50% Melee Damage and +5 Health, Battle Lust which grants +2 Health for every Melee kill, and Slugger which grants +5 Health, +10% Melee Stamina Efficiency, and +20% Melee Attack Speed, to really help make the Melee weapon a key part of Holly's build.

Best Back 4 Blood Mom Build

Back 4 Blood Mom Character
Click to enlarge

Best Mom weapons:

  • Primary weapon - Assault Rifle
  • Secondary weapon - Shotgun

Best Mom deck:

  • Two Is One And One Is None
  • Breakout
  • Second Chance
  • Copper Scavenger
  • Rolling Thunder
  • Combat Knife
  • Support Scavenger
  • Inspiring Sacrifice
  • Avenge The Fallen
  • Charitable Soul
  • Smelling Salts
  • Ridden Slayer
  • Superior Cardio
  • Cross Trainer
  • Buckshot Bruiser

Mom is a great character to focus on both offense and support for her team, with her being able to instantly revive one teammate per level, as well as having +1 Support Inventory and granting an Extra Life to her team. We have decided to go with the Two Is One And One Is None card again to allow her to swap out The Belgian Shotgun for a better alternative. You will also notice that many of the builds utilize the Combat Knife card if they don't have a Melee weapon, which gives players a Knife for Melee Attacks, which makes them stronger and more likely to kill an enemy.

Best Back 4 Blood Doc Build

Back 4 Blood Doc Character
Click to enlarge

Best Doc weapons:

  • Primary weapon - Assault Rifle
  • Secondary weapon - Sniper Rifle

Best Doc deck:

  • Combat Knife
  • Breakout
  • Second Chance
  • Fanny Pack
  • Copper Scavenger
  • Two Is One And One Is None
  • Inspiring Sacrifice
  • Battle Lust
  • Reckless Strategy
  • Smelling Salts
  • Superior Cardio
  • Poultice
  • Antibiotic Ointment
  • Support Scavenger
  • Utility Scavenger

Doc is the game's support character, with her being able to heal each teammate for 25 health once per level, as well as having a +20% Healing Efficiency boost, and a +25% Team Trauma Resistance boost. Doc works best as a character that can stand back away from the hordes and take out enemies from afar while being stocked up on healing items to ensure her teammates get through the mission.

For this reason, we've given her the Assault Rifle which is a fantastic weapon for both close and long-ranged fights, and a Sniper Rifle as a secondary weapon thanks to the Two Is One And One Is None card. Then most of her other cards are focused on either giving her more inventory space for items, or improving them, such as Fanny Pack, Smelling Salts, Poultice, Antibiotic Ointment, Support Scavenger, and Utility Scavenger.

Best Back 4 Blood Hoffman Build

Back 4 Blood Hoffman Character
Click to enlarge

Best Hoffman weapons:

  • Primary weapon - Assault Rifle
  • Secondary weapon - Shotgun

Best Hoffman deck:

  • Breakout
  • Copper Scavenger
  • Two Is One And One Is None
  • Combat Knife
  • Battle Lust
  • Grenade Pouch
  • Buckshot Bruiser
  • Ammo Pouch
  • Ridden Slayer
  • Superior Cardio
  • Ammo For All
  • Confident Killer
  • Reckless Strategy
  • Cross Trainers
  • Avenge The Fallen

Hoffman is designed as an offense-based character, with his ability being that Ridden may drop ammo when killed. Combine that with +1 Offensive Inventory and a +10% Max Team Ammo Capacity, Hoffman is here to shoot as many enemies as he can.

His deck reflects this with the Grenade Pouch which grants a further +1 Offensive Inventory slot, Ammo Pouch to further increase his Ammo Capacity by +25%, and the Confident Killer card, which grants a 1% damage boost for each Mutation killed up to 15%. This can really make taking down strong enemies such as Ogres a much easier experience.

Best Back 4 Blood Jim Build

Back 4 Blood Jim Character
Click to enlarge

Best Jim weapons:

  • Primary weapon - Assault Rifle
  • Secondary weapon - Pistol (Magnum/Desert Eagle)

Best Jim deck:

  • Copper Scavenger
  • Breakout
  • Combat Knife
  • Battle Lust
  • Tactical Vest
  • Ammo For All
  • Avenge The Fallen
  • Patient Hunter
  • Mag Carrier
  • Combat Training
  • Ammo Pouch
  • Hi-Vis Sights
  • Run And Gun
  • Ridden Slayer
  • Superior Cardio

Jim is another character that is focused on offense, with Precision kills granting a stacking 2.5% Damage boost, he also has a +25% Aim Down Sights Speed boost, and a +10% Team Weakspot Damage boost. For his weapons, we have gone with an Assault Rifle, as well as either a Magnum or Desert Eagle for long-ranged headshots.

Like Hoffman, his deck reflects the tank-like nature of his playstyle, with cards such as Tactical Best granting a 30% Rifle Ammo Capacity boost, Mag Carrier granting a 30% Pistol/SMG Ammo Capacity boost, Combat Training giving Jim a 5% Bullet Damage and 50% Bullet Penetration boost, and Run And Gun allowing Jim to shoot while sprinting.

Best Back 4 Blood Karlee Build

Back 4 Blood Karlee Character
Click to enlarge

Best Karlee weapons:

  • Primary weapon - Assault Rifle
  • Secondary weapon - SMG

Best Karlee deck:

  • Breakout
  • Combat Knife
  • Battle Lust
  • Avenge The Fallen
  • Tactical Vest
  • Cross Trainers
  • Hi-Vis Sights
  • Ridden Slayer
  • Shooting Gloves
  • Superior Cardio
  • Reload Drills
  • Ammo Pouch
  • Combat Training
  • Ammo For All
  • Run And Gun

Finally, we have Karlee, who is best suited towards quick offensive play, with the best weapons being an Assault Rifle and SMG. Alternatively, the AR could also be swapped out for a Shotgun too. Karlee can sense nearby hazards and Mutations, which really helps to identify threats to her team, as well as having +1 Quick Inventory and +50% Team Use Speed boosts.

Her deck reflects the quick run and gun style that she is best suited for, with Cross Trainers and Superior Cardio increasing her Stamina and move speed. Alongside that, cards such as Hi-Vis Sights, Shooting Gloves, Reload Drills, and Run And Gun improve her gunplay and helps make her a quick character that can run into a horde of Ridden with all guns blazing, before creating some distance between her and Mutations in order to take them out. 

Now you know all of the best Back 4 Blood builds for each character, make sure you check out all of the Back 4 Blood secrets to earn every trophy/achievement.

 

David is a freelance journalist at GGRecon. Beginning his gaming journey in 1993 SNES as an avid Super Mario World fan, his passion for games led him into journalism in 2019. When he's not cranking 90s in Pleasant Park, he can often be found playing the latest releases including Resident Evil, The Legend of Zelda, and Grand Theft Auto.

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